A newly discovered communication pathway linking far-flung nerve centers within the brain and skull, and the body beyond, could provide a new target to stop migraine pain in its tracks. Researchers have long tried to pinpoint where migraines begin in the brain, and how these one-sided, nauseating headaches induce pain and other symptoms, such as vomiting. Understanding this would help find new ways to prevent migraines from happening or at least ease the searing pain once it starts.
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— Sylvia Plath (via lunamonchtuna)
Around 8% of human DNA is made up of genetic sequences acquired from ancient viruses. These sequences, known as human endogenous retroviruses (or Hervs), date back hundreds of thousands to millions of years – with some even predating the emergence of Homo sapiens. Our latest research suggests that some ancient viral DNA sequences in the human genome play a role in susceptibility to psychiatric disorders such as schizophrenia, bipolar disorder and major depressive disorder. Hervs represent the remnants of these infections with ancient retroviruses. Retroviruses are viruses that insert a copy of their genetic material into the DNA of the cells they infect.
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Sylvia Plath // Fyodor Dostoyevsky
A 2013 study in the journal Obstetrics and Gynecology found that among more than 750,000 women, about 46% removed their ovaries at the time of hysterectomy whereas 54% didn’t. Even premenopausal women who preserve their ovaries during a hysterectomy are at increased risk of dementia and heart disease but less so, according to multiple studies.
The health risks associated with the removal of ovaries are significant.
Rocca was co-author of a 2021 Jama Network Open study that found that women under 46 who removed both of their ovaries with or without a hysterectomy had an increased risk of mild cognitive impairment and performed worse on cognitive tests 30 years later compared with women who didn’t undergo the procedure.
Another study Rocca co-wrote found that women who had ovaries removed before age 50 faced higher risks for several conditions years later, including heart disease and osteoporosis.
Other studies have linked the procedures to an increased risk of dementia, Parkinson’s disease and accelerated aging.
Partial quote. Just got this as a little news alert and it’s something I think about semi frequently because of my job. Really under discussed and kind of wild
fatima aamer bilal, from moony moonless sky’s ‘i am your mould, but the shape of you is true absence, leaving me purposeless.’
[text id: and is this not treason? / my soul belongs far more to you than it does to me.]
The constant ebb and flow of hormones that guide the menstrual cycle don't just affect reproductive anatomy. They also reshape the brain, and a new study has given us insight into how this happens. Led by neuroscientists Elizabeth Rizor and Viktoriya Babenko of the University of California Santa Barbara, a team of researchers tracked 30 women who menstruate over their cycles, documenting in detail the structural changes that take place in the brain as hormonal profiles fluctuate. The results, which are yet to be peer-reviewed but can be found on preprint server bioRxiv, suggest that structural changes in the brain during menstruation may not be limited to those regions associated with the menstrual cycle. "These results are the first to report simultaneous brain-wide changes in human white matter microstructure and cortical thickness coinciding with menstrual cycle-driven hormone rhythms," the researchers write.
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Susan Nathiel, Daughters of Madness
"to endure!"
vincent van gogh ("trees and undergrowth") robert lowell [How will the heart endure?] vincent van gogh [I must endure bad times and the waters will rise, possibly as high as the lips and possibly even higher, how can I know beforehand? But I’ll fight my fight and sell my life dearly and try to win and pull through.] rainer maria rilke [To be loved means to be consumed. To love means to radiate with inexhaustible light. To be loved is to pass away, to love is to endure.] joan didion [Not just to endure it, not just to suffer it, not just to pass through it, but to live in it.] elena ferrante [maybe not even a very orderly mind can endure the discovery of not being loved.] elena ferrante [I will give what I can give, I will take what I can take, I will endure what has to be endured.] han kang [The feeling that she had never really lived in this world caught her by surprise. It was a fact. She had never lived. Even as a child, as far back as she could remember, she had done nothing but endure.] victor frankl [What is to give light must endure burning.]