The Pursuit Of A Cure For Alzheimer's Disease Is Becoming An Increasingly Competitive And Contentious

– Noor Unnahar, Instagram account "noor_unnahar"

[TEXT ID: / [Lemons] / My father's mother loved lemons. Years after her passing, / we run out of everything, but never / lemons. / Nothing else shelters grief / better than memory. / It's my father way of saying, / even in your absence, you will be / cared by me. / END ID]

Good News Network

A Paralyzed Man Walks Again Using Device that Connects His Thoughts to His Spinal Cord

It's long been supposed that implants could connect prosthetics to the brain in a way that stimulates nervous system commands.

"It’s long been supposed that implants could connect prosthetics to the brain in a way that stimulates nervous system commands with electrical signals.

Now, this idea is closer than ever to realization in a meaningful way, as one man paralyzed from the hips down is able to walk unsupported, even up stairs, thanks to such electrical nerve stimulation.

The patient, Gert-Jan Oskam, lost all movement in his legs after suffering a spinal cord injury in a motorbike accident. After using a precursor technology to gain back a little bit of mobility, Oskam enrolled in a proof of concept study to perhaps make further advances...

Now, with an implant in his brain, when Oskam thinks about moving his legs, it sends a signal to a computer he wears in a backpack that calculates how much current to send to a new pacemaker in his abdomen. It in turn sends a signal to the older implant in his spinal cord that prompts his legs to move in a more controllable manner. A helmet with antennae helps coordinate the signals.

The scientists developing the technology and working with him detail that he can walk around 200 meters a day, and stand unassisted for around 2-3 minutes. Once, Oskam details, there was some painting that needed to be done, but no one was around to help him. With the new technology, he simply took his crutch and did it himself.

Incredibly, after less than a year, and completely unexpectedly, scientists believe the technology closed the gap in his nervous system, and he can now lift himself out of a chair, and even walk with the help of a crutch, even when the device is turned off.

The scientists are planning in the future to work with patients with paralyzed arms and hands, and even with stroke victims, as the “digital bridge” is a massive advancement in nervous system stimulation technology."

-via Good News Network, June 16, 2023. Video via NBC News, May 24, 2023

apple.news

The Crucial Decision That Can Protect Women’s Health as They Age — The Wall Street Journal

Removing ovaries with a hysterectomy might increase risk of heart disease, stroke and dementia

A 2013 study in the journal Obstetrics and Gynecology found that among more than 750,000 women, about 46% removed their ovaries at the time of hysterectomy whereas 54% didn’t. Even premenopausal women who preserve their ovaries during a hysterectomy are at increased risk of dementia and heart disease but less so, according to multiple studies.

The health risks associated with the removal of ovaries are significant.

Rocca was co-author of a 2021 Jama Network Open study that found that women under 46 who removed both of their ovaries with or without a hysterectomy had an increased risk of mild cognitive impairment and performed worse on cognitive tests 30 years later compared with women who didn’t undergo the procedure.

Another study Rocca co-wrote found that women who had ovaries removed before age 50 faced higher risks for several conditions years later, including heart disease and osteoporosis.

Other studies have linked the procedures to an increased risk of dementia, Parkinson’s disease and accelerated aging.

Partial quote. Just got this as a little news alert and it’s something I think about semi frequently because of my job. Really under discussed and kind of wild

Illuminating the brain through art and science

Joan Didion, from Blue Nights

ScienceAlert

We May Have Found a Target For Treating The Fatigue of Long COVID

Researchers have just discovered a process in fruit flies which links inflammation with impaired motor function, providing researchers with

Researchers have just discovered a process in fruit flies which links inflammation with impaired motor function, providing researchers with a potential target for treating the persistent muscle fatigue that follows many infections. Of long COVID's numerous symptoms, an intolerance to exertion could be considered one of the more debilitating. "This is more than a lack of motivation to move because we don't feel well," says Washington University developmental biologist Aaron Johnson. "These processes reduce energy levels in skeletal muscle, decreasing the capacity to move and function normally."

Continue Reading.

Sylvia Plath, from Three Women: A Poem for Three Voices [ID in alt text]

Good News Network

Owning Pets Helps Stave Off Dementia for People Over 50 Living on Their Own

Caring for a pet helps stave off cognitive decline for people over 50 who live on their own, according to a new study of almost 8,000 partic

"Caring for a pet helps stave off cognitive decline for people over 50 who live on their own, according to a new study of almost 8,000 participants.

Researchers found that pet ownership was associated with slower rates of decline in verbal memory and verbal fluency among the older adults who were living alone.

The study included 7,945 mostly-white British participants from the English Longitudinal Study of Ageing with an average age of 66.

Followed over an eight year period, more than a third of the group (35.1 percent) owned pets; about 30% of the group lived alone.

Previous studies suggested that solitary living is a risk factor for developing dementia and cognitive decline, but among those folks, raising dogs or cats was related to reduced loneliness.

Some research has found that pet ownership is associated with better verbal memory and executive function, but others failed to find any evidence.

The new research published in JAMA Network aimed to further explore the association between aging by oneself—a trend which has been on the rise over the past few decades—and pet ownership. And the results were clear.

“Pet ownership offset the associations between living alone and declining rates in verbal memory and verbal fluency,” said study corresponding author Professor Ciyong Lu, of Sun Yat-sen University in Guangzhou, China.

It was “a significant modifier” in all 3 associations—composite verbal cognition, verbal memory, and verbal fluency.

“Pet ownership was associated with slower rates of decline among older adults living alone.”

But owning a cat or dog did not make any difference for older people who lived with other people.

“These findings suggest that pet ownership may be associated with slower cognitive decline among older adults living alone.”

Prof. Lu is now calling for clinical trials that could help inform public health measures to address dementia among the elderly."

-via Good News Network, November 30, 2023

people who work/study in quantitative bio-adjacent fields, rise up. computational neuroscience where you get to see someone's thoughts in feelings in graph form??? so cool. biophysics where you can pass blood plasma through an electric field to determine whether a patient has cancer or not?? unbelievable. biomedical engineering where you can literally build a device to pump someone's heart and be the difference between their life and death??? oh my god. disease modelling, being able to predict AND prevent communities being affected by disease on a large scale through your analysis of data??? i love science