Concept: xenofiction sci-fi where the main characters are different alien beings. It’s all treated and framed as “normal” from both the audience’s and each other’s perspective, even when their behavior is obviously not something a human would do.
Eventually, we meet a human character, whose actual name appears to be “Smith the Human”, and who acts like aliens from mediocre pop sci-fi stories – like, someone goes “Oh, I’ve never met a human before!” and he responds by spouting random (technically-accurate-to-real-life) factoids about human culture and biology in a way that no real human being ever would, i.e. “Humans are social persitence hunters and apex predators – on our harsh homeworld of Terra, we evolved to form hierarchal hives or colonies, like your world’s Zoink-Ants or Frisk-Bees! We weren’t that fast over short distances, and so we caught our prey, not by ambush or by pursuit, but by simply walking, brisk jogging, and tracking our prey until the prey tired itself out, allowing us to catch it at our leisure!” He always maintains the same stilted but forceful tone of voice, devoid of any emotional content, and his facial expression never changes from “we didn’t bother to animate his face”-style dull surprise.
He wears American soldier gear and says “Humans are a Proud Warrior Race™!” without a trace of irony.
Now, one possible punchline would be that the protagonists eventually meet other humans, and it turns out that he’s the only human who’s Like That. However, I think that in order to commit to the whole “xenofiction” bit, you’d need to make every human completely identical, in exactly the same way that members of an alien species in pop sci-fi are identical. The way I personally would do it is,the loud-deadpan-weirdo routine is just an “unreliable narration” due to the perceptions of characters who aren’t familiar with humans; as a group, even if the nonhuman characters are like “Wow, they really are synchronized like a hive of Frisk-Bees!” or whatever, the humans behave exactly how an actual group of humans would behave in that kind of situation, if you read between the lines. (And, y'know, a squadron of uniformed soldiers with a CO in the background is inevitably going to act differently from a similarly-sized group of civilians; the nonhuman characters, and hence the audience, just don’t get to see how they are “normally”.)
The actual punchline is that after the “human” plot is resolved (maybe they’re antagonists, and the prior ramble about their biology proves to be a vital component?), there’s a scene where the viewpoint character is a human, and the whole situation is precisely reversed: humans look more diverse and talk like normal people, and all the nonhuman characters of each species are identical and do the loud-deadpan-weirdo thing.